drugset / Trial / NCT04841538

A Study of ES101 (PD-L1x4-1BB Bispecific Antibody) in Patients With Advanced Malignant Thoracic Tumors

NCT04841538 ↗

Phase 1/2 Withdrawn Elpiscience Biopharma, Ltd.
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety, RP2D and PK/pharmacodynamic profile of ES101 monotherapy in patients with advanced NSCLC and to further evaluate the antitumor efficacy of ES101 in advanced malignant thoracic tumors, including NSCLC and SCLC.

Timeline

Start
2021-07
Primary completion
2023-12
Completion
2024-05

Outcome

Outcome not reported

Stopped (Business): “Sponsor's clinical development strategy adjustment”

Drugs

EvaluationDrugModalityDoseRoute
Subject ES101 Unknown 0.3 mg/kg Intravenous
Subject ES101 Unknown 1 mg/kg Intravenous