drugset / Trial / NCT04844619

KDR2-2 Suspension Eyedrop in the Treatment of Neovascular Glaucoma (KDR-NVG) Trial

NCT04844619 ↗

Phase 1 Active not recruiting 40 enrolled Sun Yat-sen University
NaSingle-groupOpen-labelTreatment

Summary

The clinical trial is aimed to evaluate the anti-neovascular effect of KDR2-2 suspension eyedrop in the treatment of neovascular glaucoma. Fourty subjects would receive either 0.96 or 3.84 mg/per day/eye, in a QID fashion, ×7 days (those without complications can continue to 28 days). The anti-neovascular effect of KDR2-2 on iris neovascularization would be evaluated at day 1, day 7, day 14, day 28 after KDR2-2 usage.

Timeline

Start
2021-04-19
Primary completion
2024-12-31
Completion
2024-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject KDR2-2 Small molecule 4 mg/ml —
Subject KDR2-2 Small molecule 16 mg/ml —