drugset / Trial / NCT04846348

Topical Composition Therapy for the Treatment of Cutaneous Mastocytosis

NCT04846348 ↗

Phase 2 Terminated 1 enrolled Joseph Butterfield
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to determine the effectiveness and tolerability of a novel topical preparation for the treatment of cutaneous lesions of mastocytosis.

Timeline

Start
2021-07-26
Primary completion
2021-09-10
Completion
2021-09-10

Outcome

Outcome not reported

Stopped (Enrollment): “It was difficult to enroll patients during the pandemic. A new oral drug, Avapritinib, has since been approved for systemic mastocytosis. This medication controls skin manifestations of mastocytosis and is more convenient for patients to use.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Cromolyn Small molecule 5 % Topical
Subject Diphenhydramine Small molecule 1 % Topical
Subject trolamine salicylate Small molecule 10 % Topical