drugset / Trial / NCT04846348
Topical Composition Therapy for the Treatment of Cutaneous Mastocytosis
NaSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to determine the effectiveness and tolerability of a novel topical preparation for the treatment of cutaneous lesions of mastocytosis.
Timeline
- Start
- 2021-07-26
- Primary completion
- 2021-09-10
- Completion
- 2021-09-10
Outcome
Outcome not reported
Stopped (Enrollment): “It was difficult to enroll patients during the pandemic. A new oral drug, Avapritinib, has since been approved for systemic mastocytosis. This medication controls skin manifestations of mastocytosis and is more convenient for patients to use.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cromolyn | Small molecule | 5 % | Topical |
| Subject | Diphenhydramine | Small molecule | 1 % | Topical |
| Subject | trolamine salicylate | Small molecule | 10 % | Topical |