Comparative Study Between Nicorandil and Nifedipine for the Treatment of Preterm Labour

Phase 2 Unknown 230 enrolled Ain Shams University

RandomizedParallel-groupSingle-blindPrevention

Summary

Nicorandil (potassium channel activator) is claimed to be as effective as Nifedipine (calcium channel blocker) for tocolysis in preterm labour aim of the study: To assess the efficacy of Nicorandil compared with Nifedipine as a tocolytic agent in delaying labour for 48 hours following their administration

Timeline

Start: 2020-06-01
Primary completion: 2021-06
Completion: 2021-07-01

Publications

Wilson A, Hodgetts-Morton VA, Marson EJ, Markland AD, Larkai E, Papadopoulou A, Coomarasamy A, Tobias A, Chou D, Oladapo OT, Price MJ, Morris K, Gallos ID. Tocolytics for delaying preterm birth: a network meta-analysis (0924). Cochrane Database Syst Rev. 2022 Aug 10;8(8):CD014978. doi: 10.1002/14651858.CD014978.pub2.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Nicorandil	Other / unclassified	10 mg	Oral
Subject	Nifedipine	Other / unclassified	10 mg	Oral

Indications

No indication recorded.