drugset / Trial / NCT04849715

A Study of Parsaclisib, a PI3Kδ Inhibitor, in Combination With Bendamustine and Rituximab in Patients With Newly Diagnosed Mantle Cell Lymphoma

NCT04849715

Phase 3 Withdrawn Incyte Corporation
RandomizedParallel-groupDouble-blindTreatment

Summary

This is a Phase 3, double-blind, randomized, placebo-controlled, multicenter study of parsaclisib plus BR versus placebo plus BR as first-line treatment of participants with newly diagnosed MCL.

Timeline

Start
2022-03-11
Primary completion
2030-08-15
Completion
2034-07-07

Drugs

EvaluationDrugModalityDoseRoute
Comparator Parsaclisib Small molecule Oral
Comparator Bendamustine Small molecule Intravenous
Comparator Rituximab Monoclonal antibody Intravenous

Indications