drugset / Trial / NCT04850651
Effect of Fluconazole on the Pharmacokinetics of Pyrotinib in Healthy Subjects
NaSingle-groupOpen-labelOther
Summary
The primary objective of the study is to evaluate the effect of fluconazole on pharmacokinetics of pyrotinib tablet for oral administration in healthy Chinese adult subjects. The secondary objective of the study is to compare the safety of pyrotinib alone and co-administered with fluconazole.
Timeline
- Start
- 2021-04-16
- Primary completion
- 2021-05-17
- Completion
- 2021-05-17
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fluconazole | Small molecule | 200 mg | Oral |
| Subject | Pyrotinib | Small molecule | 80 mg | Oral |
Indications
No indication recorded.