drugset / Trial / NCT04856319

The Effect of Pre-operative Single Dose Antibiotic Prophylaxis on the Post-operative Implant Success

NCT04856319

Unknown 50 enrolled Biruni University
RandomizedParallel-groupDouble-blindTreatment

Summary

There is no consensus on antibiotic prophylaxis in dental implant applications, and its necessity is controversial. Current reports on antibiotic use are insufficient. Also, other than antibiotic prophylaxis, data that may affect the post-operative situation such as the patient's gender, age, smoking, duration of surgery, length of the operation field, flap design have not been evaluated comprehensively. This study aims to evaluate post-operative complications, implant success, and implant stability in 50 individuals: preoperative single dose of 2 g amoxicillin + clavulanic acid (25) and placebo (25).

Timeline

Start
2022-09-01
Primary completion
2023-09-01
Completion
2023-12-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Amoxicillin Other / unclassified Oral
Comparator clavulanic acid Small molecule Oral

Indications