drugset / Trial / NCT04857892
A Relative Bioavailability and Food-Effect Study of the Fixed Dose Combination of GSK3640254 and Dolutegravir (DTG) in Healthy Participants
RandomizedCrossoverOpen-labelTreatment
Summary
This is a two part study to compare the relative bioavailability (BA) of 2 fixed dose combinations (FDCs) of GSK3640254/DTG with GSK3640254 and DTG administered together as single agents (Part 1) and to assess the effect of food on the pharmacokinetic (PK) of the selected FDC of GSK3640254/DTG (Part 2).
Timeline
- Start
- 2021-04-21
- Primary completion
- 2021-09-10
- Completion
- 2021-09-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | DTG | Unknown | 50 mg | Oral |
| Subject | FIPRAVIRIMAT | Small molecule | 150 mg | Oral |
| Subject | FIPRAVIRIMAT | Small molecule | — | Oral |