Study on the Tolerability, Pharmacodynamics and Pharmacokinetics of GST-HG141 Tablets

Summary

To Evaluate the Tolerability, Pharmacodynamics and Pharmacokinetics of GST-HG141 Tablets in Multiple-center, Randomized, Double-blind, Placebo-controlled Multiple-dose, Multiple-administration Study in Patients With Chronic Hepatitis B (CHB)

Timeline

Start

2021-05-31

Primary completion

2022-02-23

Completion

2022-03-14

Publications

• Wu M, Mai J, Zhang H, Zhang G, Mao J, Tang Y, Yan W, Wu W, Hou J, Liang X, Liu Z, Ding Y, Niu J. Safety, pharmacokinetics, and antiviral efficacy of the novel capsid assembly modulator GST-HG141 in patients with chronic hepatitis B: a phase 1 trial with a randomized, placebo-controlled design. Virol J. 2024 Dec 20;21(1):328. doi: 10.1186/s12985-024-02584-8.

Drugs

Indications