drugset / Trial / NCT04871828

The Efficacy of Leukotriene Inhibitor in Adult Patients With Moderate SARS-COV-2 Symptoms (COVID19)

NCT04871828

RandomizedParallel-groupTriple-blindTreatment

Summary

There is an urgent need to explore therapeutic options for SARS-CoV-2 in order to face the pandemic. The selected intervention was based on that zafirlukast will have dual effect; first it will block the virus replication through inhibiting the COVID19 helicase that is involved in virus replication and secondly by reducing the inflammation through antagonizing the leukotriene receptor. The purpose of this study is to evaluate the clinical efficacy and safety of Leukotriene receptor antagonist in the treatment of moderate cases of COVID-19 patients.

Timeline

Start
2021-02-28
Primary completion
2021-09
Completion
2021-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Zafirlukast Small molecule 20 mg Oral

Indications

No indication recorded.