drugset / Trial / NCT04872400
Acute Application of Antibiotic Powder in Open Fracture Wounds
Phase 4
Completed
20 enrolled
University of Colorado, Denver
Denver Health and Hospital Authority · collab
RandomizedParallel-groupSingle-blindPrevention
Summary
The purpose of this study is to help determine the best treatment for severe injures like open fracture wounds. Some broken bone injuries can be more likely to get an infection. It is mostly due to the way they were injured. Surgical site infection in the orthopedic surgery population is a big public health issue. Wound infections result in both longer length of hospital stay and total cost of care. This study will be using an antibiotic called Vancomycin or Tobramycin in a powder form.
Timeline
- Start
- 2021-06-14
- Primary completion
- 2023-09-30
- Completion
- 2023-09-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tobramycin | Small molecule | 1.2 g | Topical |
| Subject | Vancomycin | Other / unclassified | 1 g | Topical |