drugset / Trial / NCT04874480
Tegavivint for the Treatment of Relapsed or Refractory Leukemia
NaSingle-groupOpen-labelTreatment
Summary
This phase I trial is to find out the best dose and side effects of tegavivint in treating patients with leukemia that has come back (relapsed) or does not response to treatment (refractory). Tegavivint may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving tegavivint in combination with decitabine may help control the disease.
Timeline
- Start
- 2021-09-27
- Primary completion
- 2027-02-02
- Completion
- 2027-02-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Decitabine | Small molecule | — | Intravenous |
| Subject | Tegavivint | Small molecule | — | Intravenous |