drugset / Trial / NCT04875676
Immunogenicity & Safety Study of Adenovirus Type 5 (AD5) Based Oral Norovirus Vaccines
Non-randomizedSequentialOpen-labelPrevention
Summary
To evaluate the immunogenicity of VXA-G1.1-NN with repeat-dose administration at Day 1 and varying boost schedules (Week 4, 8 or 12 post initial dose) in healthy adults aged 18-55, inclusive, and to assess the safety and tolerability of VXA- G1.1-NN with repeat-dose administration at varying boost schedules (Week 4, 8 or 12) in healthy adults aged 18-55, inclusive
Timeline
- Start
- 2021-04-30
- Primary completion
- 2021-10-30
- Completion
- 2022-02-16
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | VXA-G1.1-NN | Vaccine | 1e+10 iu | Oral |