drugset
drugset / Trial / NCT04876807

A Study to Evaluate the Effect of an Acidic Formulation of Acalabrutinib (ACP-196), Acidic Beverage, or Grapefruit Juice on the Pharmacokinetics (PK) of ACP-196 Alone and Coadministered With Omeprazole

NCT04876807 ↗

Phase 1 Completed 36 enrolled Acerta Pharma BV
Non-randomizedSequentialOpen-labelTreatment

Summary

This study will evaluate the effect of an acidic formulation of Acalabrutinib (ACP-196), acidic beverage, or grapefruit Juice on the PK of ACP-196 alone and coadministered with omeprazole.

Timeline

Start
2016-01-28
Primary completion
2016-03-15
Completion
2016-03-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Acalabrutinib Small molecule — Oral
Subject Omeprazole Other / unclassified — —

Indications

No indication recorded.