drugset / Trial / NCT04885998

AMG 757 and AMG 404 in Subjects With Small Cell Lung Cancer (SCLC)

NCT04885998

Phase 1 Completed 23 enrolled Amgen
Non-randomizedSequentialOpen-labelTreatment

Summary

The main purpose of this study is to evaluate the safety, tolerability, and recommended phase 2 target dose of tarlatamab in combination with AMG 404.

Timeline

Start
2021-09-27
Primary completion
2023-07-12
Completion
2024-09-11

Drugs

EvaluationDrugModalityDoseRoute
Subject AMG 404 Monoclonal antibody Intravenous
Subject Tarlatamab Protein / enzyme biologic Intravenous