drugset

drugset / Trial / NCT04891861

Restart TICrH Alpha Pilot Protocol, Restarting DOACs After Traumatic Intracranial Hemorrhage

NCT04891861 ↗

Phase 3 Unknown 100 enrolled University of Texas at Austin University of Kansas · collab

RandomizedParallel-groupSingle-blindPrevention

Summary

Randomized pilot trial of restarting DOACs at 1 week versus 4 weeks after traumatic intracranial hemorrhage

Timeline

Start: 2021-07-01
Primary completion: 2023-07-01
Completion: 2023-07-01

Publications

Results Milling TJ Jr, Warach S, Johnston SC, Gajewski B, Costantini T, Price M, Wick J, Roward S, Mudaranthakam D, Dula AN, King B, Muddiman A, Lip GYH. Restart TICrH: An Adaptive Randomized Trial of Time Intervals to Restart Direct Oral Anticoagulants after Traumatic Intracranial Hemorrhage. J Neurotrauma. 2021 Jun 1;38(13):1791-1798. doi: 10.1089/neu.2020.7535. Epub 2021 Apr 6.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Apixaban	Small molecule	—	—

Indications