drugset / Trial / NCT04897542

Gallium-68 NODAGA-JR11 PECT/CT in Neuroendocrine Tumors

NCT04897542 ↗

NaSingle-groupOpen-labelDiagnostic

Summary

NODAGA-JR11 is a novel somatostatin receptor antagonist, while Gallium-68 DOTATATE is a typical somatostatin receptor agonist. This study is to evaluate the lesion detection ability of Gallium-68 NODAGA-JR11 for the diagnostic imaging of metastatic, well-differentiated neuroendocrine tumors using positron emission tomography / computed tomography (PET/CT). The results will be compared between antagonist Gallium-68 NODAGA-JR11 and agonist Gallium-68 DOTATATE in the same group of patients.

Timeline

Start
2020-12-01
Primary completion
2023-12-01
Completion
2023-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Gallium-68 NODAGA-JR11 Diagnostic / imaging agent 40 ug Intravenous
Subject Gallium-68 NODAGA-JR11 Diagnostic / imaging agent 150 mbq Intravenous
Subject Gallium-68 NODAGA-JR11 Diagnostic / imaging agent 200 mbq Intravenous