drugset / Trial / NCT04897542
Gallium-68 NODAGA-JR11 PECT/CT in Neuroendocrine Tumors
Phase 0
Unknown
100 enrolled
First Affiliated Hospital of Fujian Medical University
Peking Union Medical College Hospital · collab
NaSingle-groupOpen-labelDiagnostic
Summary
NODAGA-JR11 is a novel somatostatin receptor antagonist, while Gallium-68 DOTATATE is a typical somatostatin receptor agonist. This study is to evaluate the lesion detection ability of Gallium-68 NODAGA-JR11 for the diagnostic imaging of metastatic, well-differentiated neuroendocrine tumors using positron emission tomography / computed tomography (PET/CT). The results will be compared between antagonist Gallium-68 NODAGA-JR11 and agonist Gallium-68 DOTATATE in the same group of patients.
Timeline
- Start
- 2020-12-01
- Primary completion
- 2023-12-01
- Completion
- 2023-12-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Gallium-68 NODAGA-JR11 | Diagnostic / imaging agent | 40 ug | Intravenous |
| Subject | Gallium-68 NODAGA-JR11 | Diagnostic / imaging agent | 150 mbq | Intravenous |
| Subject | Gallium-68 NODAGA-JR11 | Diagnostic / imaging agent | 200 mbq | Intravenous |