drugset / Trial / NCT04899778

Do Oral Contraceptives Protect Against ACL Injuries in Female Athletes

NCT04899778 ↗

Phase 4 Completed 73 enrolled Cedars-Sinai Medical Center
Non-randomizedParallel-groupOpen-labelPrevention

Summary

The purpose of this research study is to examine the impact of one type of commonly used birth control pill on blood levels of relaxin and measure changes in knee movement to determine whether there are changes in joint instability (indicating the knee is less stable) that may predispose female athletes to injury. Women not on hormonal birth control will also be enrolled to analyze differences between athletes on and not on birth control and to evaluate typical relaxin levels and knee laxity when birth control pills are not used.

Timeline

Start
2021-09-29
Primary completion
2023-11-20
Completion
2024-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject norethindrn a-e estradiol-iron Unknown — Oral

Indications