drugset / Trial / NCT04903223
Liver Adiposity Effects on Pediatric Statin
Non-randomizedParallel-groupOpen-labelTreatment
Summary
Single center, open-label, prospective investigation to quantify the effects hepatocellular fat has on hepatic statin transport and response in children and adolescents in obese and non-obese children and adolescents 8-21 years of age with normal, wild-type SLCO1B1 c.521TT genotype that are dosed rosuvastatin
Timeline
- Start
- 2021-04-01
- Primary completion
- 2026-10-30
- Completion
- 2027-03-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Rosuvastatin | Small molecule | 10 mg | — |