drugset / Trial / NCT04905173

Comparison of Squat-to-Stand Maneuver With Amyl Nitrite, Valsalva, and Exercise Stress Echocardiography in Inducing Latent Left Ventricular Outflow Obstruction in Hypertrophic Cardiomyopathy

NCT04905173 ↗

Withdrawn Mayo Clinic
NaSingle-groupOpen-labelDiagnostic

Summary

The purpose of this study is to assess the effectiveness of squat-to-stand maneuver in eliciting left ventricular outflow gradients in patients with Hypertrophic Cardiomyopathy (HCM) compared to Valsalva, amyl nitrite inhalation, and exercise stress echocardiogram (ESE).

Timeline

Start
2021-11
Primary completion
2022-05
Completion
2022-05

Outcome

Outcome not reported

Stopped: “The decision was made by study team to pursue this as a quality project instead.”

Drugs

EvaluationDrugModalityDoseRoute
Background Amyl Nitrite Small molecule — Inhaled