drugset / Trial / NCT04906902

Acalabrutinib in CNSL

NCT04906902

Phase 1/2 Active not recruiting 49 enrolled Dana-Farber Cancer Institute
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This research study is a Phase 1/2 clinical trial testing the safety, tolerance and efficacy of the drug Acalabrutinib for people with recurrent or refractory central nervous system lymphoma (CNSL).

Timeline

Start
2021-08-23
Primary completion
2025-11-06
Completion
2027-01-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Acalabrutinib Small molecule 200 mg Oral
Subject Acalabrutinib Small molecule 300 mg Oral
Subject Acalabrutinib Small molecule 400 mg Oral