drugset / Trial / NCT04906915

Effect of Ketamine Assisted Analgesia on Oxygen Supply and Oxygen Consumption in Patients After Cardiac Surgery

NCT04906915 ↗

NaSingle-groupOpen-labelTreatment

Summary

After cardiopulmonary bypass heart surgery, with the rewarming of body temperature, the metabolic capacity of the body is enhanced, the microcirculation is opened, and tissue perfusion is increased. At the same time, the body pays off the oxygen debt formed by the low temperature and reduced blood flow in cardiopulmonary bypass, so that the tissue oxygen demand increases and oxygen consumption increases.Analgesia and sedation are important treatment measures for patients after cardiopulmonary bypass. S-isomer of ketamine and eselamine enhanced the sedation and enhanced the analgesic effect, but whether it can improve the imbalance of oxygen supply and oxygen consumption after cardiopulmonary bypass is unknown.

Timeline

Start
2021-05-08
Primary completion
2022-05
Completion
2022-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketamine Small molecule — —

Indications

No indication recorded.