drugset / Trial / NCT04908111
A Trial of ChAdOx1 and MVA Vaccines Against MAGE-A3 and NY-ESO-1
RandomizedParallel-groupOpen-labelTreatment
Summary
This clinical trial is looking at two new vaccines called ChAdOx1-MAGEA3-NYESO, MVA-MAGEA3 and MVA-NYESO given with patients' standard of care treatment (chemotherapy and an immune checkpoint inhibitor).
Timeline
- Start
- 2021-10-15
- Primary completion
- 2024-09-18
- Completion
- 2026-10-16
Outcome
Outcome not reported
Stopped (Enrollment): “Sponsor has decided to permanently close recruitment”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ChAdOx1-MAGEA3-NYESO | Vaccine | 5e+10 unknown | Intramuscular |
| Subject | MVA-MAGEA3 | Vaccine | 1.3e+08 unknown | Intramuscular |
| Subject | MVA-NYESO | Vaccine | 1.5e+08 unknown | Intramuscular |