drugset / Trial / NCT04908800
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of KRP-A218 in Healthy Subjects
RandomizedSequentialDouble-blindTreatment
Summary
This first-in-human study has three parts. In Parts A and B, the safety, tolerability, and pharmacokinetics (PK) will be evaluated following administration of single and multiple doses of KRP-A218, including food-effect. In Part C, the drug-drug interaction (DDI) with itraconazole will be evaluated.
Timeline
- Start
- 2021-05-27
- Primary completion
- 2022-04-21
- Completion
- 2022-04-21
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Itraconazole | Small molecule | 10 mg/ml | Oral |
| Subject | KRP-A218 | Unknown | — | Oral |
Indications
No indication recorded.