Clinical Study on Huatuo Zaizao Pills for Post-stroke Treatment

Phase 4 Completed 80 enrolled Xiyuan Hospital of China Academy of Chinese Medical Sciences

RandomizedParallel-groupSingle-blindTreatment

Summary

The purpose of this study was to evaluate the improvement of limb motor function and nerve function of patients with HTZZ during stroke rehabilitation. A total of 80 subjects will be randomly assigned to Huatuo Zaizao pill group or the control group.

Timeline

Start: 2021-05-31
Primary completion: 2023-06-20
Completion: 2023-09-30

Outcome

Met primary endpoint

paper significant improvements in MAS, NIHSS, FM, and BI scores following 6 and 12 weeks of treatment PMID 40232598 ↗

Publications

Ding YQ, Zhao D, Chen X, Yuan HM, Mao LJ. Effect of Huatuo Zaizao Pill on Neurological Function and Limb Motor Recovery in Ischemic Stroke Patients During Convalescence: An Open-Labelled, Randomized Controlled Trial. Chin J Integr Med. 2025 Jun;31(6):483-489. doi: 10.1007/s11655-025-3928-4. Epub 2025 Apr 15.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Huatuo Zaizao Pills	Traditional medicine (herbal / TCM)	8 g	Oral