drugset / Trial / NCT04913285

A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

NCT04913285

Phase 1 Active not recruiting 400 enrolled Pierre Fabre Laboratories
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of KIN-2787 in adults with BRAF/NRAS-mutated advanced or metastatic solid tumors.

Timeline

Start
2021-08-04
Primary completion
2028-11-30
Completion
2029-03-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Binimetinib Small molecule Oral
Subject EXARAFENIB Small molecule Oral