drugset / Trial / NCT04913831

Effects of Cerebrolysin on Level of Consciousness and Brain Metabolism in Disorder of Consciousness After Stroke: Single Center Randomized Controlled Study

NCT04913831

Phase 4 Unknown 30 enrolled Yonsei University
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study was to determine the effect of stroke on post-stroke level of consciousness through a double-blind, placebo-controlled, randomized study design. And Brain 18F-FDG PET was used to reveal the mechanism of recovery after cerebrolysin administration. Thirty patients with chronic stroke patients with minimal consciousness (MCS) or vegetative human (VS) level of consciousness disorder in the revised coma recovery scale were enrolled. Thirty patients were randomly divided into a Cerebrolysin group and a placebo group.

Timeline

Start
2021-06
Primary completion
2024-03
Completion
2024-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Cerebrolysin Peptide 20 ml Intravenous

Indications