drugset

drugset / Trial / NCT04916522

The COlchicine HypERtENsion Trial

NCT04916522 ↗

Phase 2 Active not recruiting 150 enrolled Herlev and Gentofte Hospital University of Copenhagen · collab

RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study to investigate the effects of colchicine on measures of vascular and cardiac function in patients with hypertension.

Timeline

Start: 2021-08-10
Primary completion: 2026-01
Completion: 2026-01

Publications

Langhoff AF, Johansen ND, Frimodt-Moller M, Sajadieh A, Schramm TK, Jepps TA, Biering-Sorensen T. A Randomized Trial to Investigate the Effects of Low-Dose Colchicine in Patients with Hypertension: Rationale and Design of the COlchicine and HypERtENsion Trial (COHERENT). J Clin Hypertens (Greenwich). 2026 Jun;28(6):e70296. doi: 10.1111/jch.70296.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Colchicine	Small molecule	0.5 mg	—

Indications