drugset / Trial / NCT04925960

Oral Epalrestat Therapy in Pediatric Subjects With PMM2-CDG

NCT04925960

Phase 3 Terminated 42 enrolled Maggie's Pearl, LLC
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This is a prospective, single-center, randomized, double-blind, placebo-controlled study designed to assess the safety, tolerability, and clinical and metabolic improvement of pediatric subjects with PMM2-CDG on oral epalrestat therapy vs. placebo.

Timeline

Start
2022-11-10
Primary completion
2025-02-28
Completion
2025-02-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Epalrestat Small molecule Oral