drugset / Trial / NCT04925986

Sitravatinib Plus Pembrolizumab in Patients With Advanced Treatment-Naïve PD-L1+ Non-Squamous NSCLC

NCT04925986

Phase 2 Terminated 9 enrolled Sarah Goldberg Mirati Therapeutics Inc. · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a multicohort phase 2 study to evaluate the efficacy of pembrolizumab combined with the investigational drug sitravatinib in the frontline treatment of advanced, non-squamous PD-L1 positive NSCLC.

Timeline

Start
2022-02-10
Primary completion
2023-06-22
Completion
2023-10-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Pembrolizumab Monoclonal antibody 200 mg Intravenous
Subject Sitravatinib Small molecule 100 mg Oral