Tau PET Imaging With 18F-T807(AV1451) in Neurodegenerative Disorders

Summary

Alzheimer's disease, Parkinson's disease, and Huntington's disease are common neurodegenerative diseases. Tau is a microtubule-associated protein, and aggregated tau resulting from hyperphosphorylation is a pathological feature of a group of neurodegenerative diseases known as tauopathies. The 18F-T807 (AV1451) molecular probe is a novel molecularly targeted imaging agent that exhibits high affinity and good selectivity for tau.

Timeline

Start

2021-11-01

Primary completion

2024-12-01

Completion

2024-12-01

Drugs

Indications