Evaluation of Myocardial Reperfusion After Primary PCI in Patients With High Platelet Reactivity Treated by Cangrelor or Not

Summary

This study aims to evaluate the impact on myocardial reperfusion and residual thrombotic burden of adding Cangrelor -a potent and immediate P2Y12 inhibitor- to ticagrelor in primary PCI patients with high on ticagrelor platelet reactivity compared to standard of care with ticagrelor alone.

Timeline

Start

2021-06-08

Primary completion

2023-03-31

Completion

2023-03-31

Publications

• Results V Roule, R Stettler, K Blanchart, M Bignon, A Lemaitre, C Peron, P Guedeney, M Zeitouni, L Schwob, R Sabatier, G Montalescot, J J Parienti, F Beygui, Cangrelor use in ticagrelor-loaded ST-elevation myocardial infarction patients with high residual platelet reactivity: a randomized controlled trial, European Heart Journal, Volume 45, Issue Supplement_1, October 2024, ehae666.1637, https://doi.org/10.1093/eurheartj/ehae666.1637

Drugs

Indications