drugset

drugset / Trial / NCT04931095

The Impact of Oral Cannabis Administration and Co-Administration of Alcohol on Impairment

NCT04931095 ↗

Phase 1 Completed 60 enrolled Johns Hopkins University National Institute on Drug Abuse (NIDA) · collab

RandomizedCrossoverDouble-blindBasic science

Summary

This study will evaluate the individual and interactive effects of oral cannabis and alcohol on subjective and behavioral measures of impairment.

Timeline

Start: 2022-02-17
Primary completion: 2025-08-15
Completion: 2025-08-15

Publications

Zamarripa CA, Lin S, Klausner M, Rastogi K, Roche DJO, Novak M, Antoine D, Wolinsky D, Marcotte TD, Weerts EM, Vandrey R, Spindle TR. Impact of Cannabis Edibles Combined With Alcohol on Driving, Field Sobriety Performance, and Subjective Effects: A Within-Participant Crossover Trial. JAMA Netw Open. 2026 May 1;9(5):e269842. doi: 10.1001/jamanetworkopen.2026.9842.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Alcohol	Other / unclassified	—	Oral
Subject	Δ9-tetrahydrocannabinol	Unknown	0 mg	Oral
Subject	Δ9-tetrahydrocannabinol	Unknown	10 mg	Oral
Subject	Δ9-tetrahydrocannabinol	Unknown	25 mg	Oral

Indications