drugset / Trial / NCT04931225
LANdiolol MIcrocirculatory Effects During Septic chOc (MILANOS)
RandomizedParallel-groupOpen-labelTreatment
Summary
The objectives of this study are to evaluate the effect of continuous intravenous Landiolol injection (from 0.5 to 10 µg/kg/min during 12 hours ) up to a 15% decrease in Heart Rate (HR) on microcirculatory vascular reactivity vs. usual tachycardia management and evaluate the hemodynamic effects of Landiolol vs. usual management in patients with septic shock.
Timeline
- Start
- 2022-07-18
- Primary completion
- 2026-07
- Completion
- 2026-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Landiolol | Small molecule | — | Intravenous |