drugset / Trial / NCT04934618

A Phase II Study of Carelizumab Combined With Irinotecan and Apatinib of Second-line Treatment for Advanced Gastric Cancer

NCT04934618

Phase 2 Unknown 85 enrolled Nanfang Hospital, Southern Medical University
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study was to evaluate the overall survival time (OS), objective remission rate(ORR), progression-free survival time(PFS), disease control rate(DCR)of Carelizumab combined with irinotecan and apatinib for the second-line treatment of locally advanced unresectable, recurrent or metastatic adenocarcinoma of stomach and gastroesophageal junction. At the same time, the safety and tolerance of the scheme were preliminarily evaluated.

Timeline

Start
2020-05-19
Primary completion
2023-05-19
Completion
2025-05-19

Drugs

EvaluationDrugModalityDoseRoute
Subject Carelizumab Unknown
Subject Irinotecan Small molecule
Subject Rivoceranib Small molecule

Indications