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drugset / Trial / NCT04937634

Pharmacokinetic Study of Melphalan in Pediatric Hematopoietic Stem Cell Transplantation

NCT04937634 ↗

Phase 1 Unknown 20 enrolled Seoul National University Hospital National Institute of Food and Drug Safety Evaluation (Republic of Korea) · collab

NaSingle-groupOpen-labelTreatment

Summary

This is an investigator-initiated clinical trial to analysis melphalan pharmacokinetics in pediatric hematopoietic stem cell transplantation patients.

Timeline

Start: 2020-09-11
Primary completion: 2023-09
Completion: 2023-09

Publications

Choi JY, Kim B, Park HJ, Kim BK, Hong KT, Lee S, Lee S, Kang HJ. Population Pharmacokinetics of Melphalan in Pediatric Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation with Various Conditioning Regimens. Eur J Drug Metab Pharmacokinet. 2026 Jul;51(4):391-400. doi: 10.1007/s13318-026-01000-6. Epub 2026 Apr 29.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Melphalan	Small molecule	50 mg/m2	—

Indications