Probiotic in Dry Eye Syndromes

Summary

This study will evaluate efficacy and safety of systemic and ophthalmic probiotic from bacterial lysate of Lactobacillus sakei on microbiota, immunological and clinical outcomes of patients with Dry Eye Syndrome.

Timeline

Start

2021-07-01

Primary completion

2022-06-30

Completion

2022-07-30

Publications

• Heydari M, Kalani M, Ghasemi Y, Nejabat M. The Effect of Ophthalmic and Systemic Formulations of Latilactobacillus sakei on Clinical and Immunological Outcomes of Patients With Dry Eye Disease: A Factorial, Randomized, Placebo-controlled, and Triple-masking Clinical Trial. Probiotics Antimicrob Proteins. 2024 Jun;16(3):1026-1035. doi: 10.1007/s12602-023-10079-1. Epub 2023 May 31.

Drugs

Indications