drugset / Trial / NCT04941911
A Feasibility Study of Octreotide Infusion During Liver Transplant.
Phase 2
Unknown
30 enrolled
University College, London
National Institute for Health Research, United Kingdom · collab
RandomizedParallel-groupQuadruple-blindOther
Summary
The purpose of the study is to determine whether an octreotide infusion during liver transplantation improves renal outcomes, intraoperative blood pressure and reduces haemorrhage and transfusion requirement.
Timeline
- Start
- 2022-05-27
- Primary completion
- 2023-10-31
- Completion
- 2024-01-31
Publications
- Background Fabes J, Ambler G, Shah B, Williams NR, Martin D, Davidson BR, Spiro M. Protocol for a prospective double-blind, randomised, placebo-controlled feasibility trial of octreotide infusion during liver transplantation. BMJ Open. 2021 Dec 2;11(12):e055864. doi: 10.1136/bmjopen-2021-055864.
- Coppack KES, Kantsedikas I, Brodkin E, Loh EN, Ambler G, Moonesinghe SR, Fabes J, Hannon V, Spiro M, Wagstaff D. Understanding recruitment to a randomised controlled trial (RCT) during liver transplantation: an observational mixed-methods Study Within A Trial (SWAT). BMJ Open. 2026 Jan 7;16(1):e104310. doi: 10.1136/bmjopen-2025-104310.
- Zhu X, Qiao Y, Liu W, Zhu J, Shen H, Huang Y, Lai R, Nan G, Shu M, Jia J. The Scar-suppressing Efficiency of Three Sutures with Different Degradation Rates: A Prospective Split-Scar Study. Aesthetic Plast Surg. 2026 May;50(9):3497-3506. doi: 10.1007/s00266-025-05288-8. Epub 2025 Oct 23.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Octreotide | Peptide | 100 ug | Intravenous |