drugset / Trial / NCT04944524
Comparison of Tofacitinib and Methotrexate in the Maintained Treatment of GPA
RandomizedParallel-groupSingle-blindTreatment
Summary
The aim of this study is to identify the optimal maintenance therapy for granulomatosis with polyangiitis (GPA) by comparing the MTX (standard regimen) with Tofacitinib in terms of efficacy, i.e. in preventing relapses.
Timeline
- Start
- 2021-07-01
- Primary completion
- 2024-07-01
- Completion
- 2024-07-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Methotrexate | Small molecule | 20 mg | — |
| Subject | Tofacitinib | Small molecule | 5 mg | — |