drugset / Trial / NCT04946864

A Study to Investigate the Safety, Tolerability, of APG-2575 as a Single Agent or in Combination for Breast Cancer

NCT04946864

Phase 1/2 Suspended 65 enrolled Ascentage Pharma Group Inc.
Non-randomizedSequentialOpen-labelTreatment

Summary

This is a multi-center, open-label, phase Ib/II study of APG-2575 as a single agent in patients with advanced solid tumors or in combination with anti-cancer agents such as CDK 4/6 inhibitor palbociclib in patients with ER+/HER2- metastatic breast cancer (mBC) who have progressed or relapsed after first line therapy

Timeline

Start
2021-08-13
Primary completion
2024-08-12
Completion
2024-10-01

Drugs

EvaluationDrugModalityDoseRoute
Subject APG-2575 Small molecule
Background Palbociclib Small molecule

Indications