drugset / Trial / NCT04954014
Pilot Study of Single Dose Bevacizumab as Treatment for Acute Respiratory Distress Syndrome (ARDS) in COVID-19 Patients
RandomizedParallel-groupOpen-labelTreatment
Summary
Our hypothesis is that treating ARDS caused by COVID-19 with bevacizumab improves mortality. This is a phase II, multi-centered, randomized, open label, two-armed clinical trial to study the safety and efficacy of bevacizumab in COVID-19 positive patients who consequently developed ARDS (acute respiratory distress syndrome) and who have previously received anti-viral and anti-inflammatory treatment.
Timeline
- Start
- 2020-09-01
- Primary completion
- 2021-08-31
- Completion
- 2021-08-31
Outcome
Outcome not reported
Stopped (Business): “Lack of financing, lack of COVID19 patients in the ICU.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bevacizumab | Monoclonal antibody | 7.5 mg/kg | — |