drugset / Trial / NCT04958434

Study of TST005 in Patients With Locally Advanced or Metastatic Solid Tumors

NCT04958434 ↗

Phase 1 Terminated 19 enrolled Suzhou Transcenta Therapeutics Co., Ltd.
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This is an open label Phase 1, first-in-human (FIH) study of TST005, a bi-specific antibody consisting of a PD-L1 monoclonal antibody (mAb) and a transforming growth factor beta (TGF-β) trap in subjects with locally advanced or metastatic cancers

Timeline

Start
2021-06-11
Primary completion
2023-09-30
Completion
2023-09-30

Outcome

Outcome not reported

Stopped: “Corporate Decision”

Drugs

EvaluationDrugModalityDoseRoute
Subject TST005 Unknown 1 mg/kg Intravenous