drugset / Trial / NCT04958434
Study of TST005 in Patients With Locally Advanced or Metastatic Solid Tumors
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This is an open label Phase 1, first-in-human (FIH) study of TST005, a bi-specific antibody consisting of a PD-L1 monoclonal antibody (mAb) and a transforming growth factor beta (TGF-β) trap in subjects with locally advanced or metastatic cancers
Timeline
- Start
- 2021-06-11
- Primary completion
- 2023-09-30
- Completion
- 2023-09-30
Outcome
Outcome not reported
Stopped: “Corporate Decision”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | TST005 | Unknown | 1 mg/kg | Intravenous |