drugset / Trial / NCT04963764
Procalcitonin to Reduce Antibiotic Use in Pediatric Pneumonia
Phase 0
Completed
5 enrolled
Ann & Robert H Lurie Children's Hospital of Chicago
Children's Hospital Medical Center, Cincinnati · collabChildren's Hospital of Philadelphia · collabUniversity of Utah · collab
RandomizedParallel-groupQuadruple-blindOther
Summary
This pilot study will evaluate study processes and feasibility of a future large-scale clinical trial that proposes to test whether low-risk children managed as outpatients with community-acquired pneumonia (CAP) and procalcitonin (PCT) levels \<0.25 ng/mL treated with placebo have a similar clinical response to those treated with antibiotics and fewer adverse effects.
Timeline
- Start
- 2021-10-18
- Primary completion
- 2022-05-27
- Completion
- 2022-05-27
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amoxicillin | Other / unclassified | 80 mg/kg | Oral |
| Comparator | Amoxicillin | Other / unclassified | 100 mg/kg | Oral |