drugset / Trial / NCT04968002

Application of Pablizumab Combined With Apatinib and Chemotherapy in Resectable Non-small Cell Lung Cancer: A Prospective, Single Arm, Single Center Phase II Clinical Study of Neoadjuvant Therapy

NCT04968002

NaSingle-groupOpen-labelTreatment

Summary

This is a prospective, single arm, single center clinical study to determine the efficacy and safety of pablizumab combined with apatinib and neoadjuvant chemotherapy in patients with stage iia-iiia non-small cell lung cancer. No EGFR mutation or ALK gene translocation was found in the untreated patients with NSCLC stage IIa-IIIb diagnosed by imaging, histopathology or cytology. After informed consent is signed by the patients. The patients were treated according to the protocols. The patients were followed up from adjuvant treatment and follow-up to relapse free survival until disease progression, withdrawal of informed consent, loss of follow-up or death.

Timeline

Start
2021-08-01
Primary completion
2022-08-01
Completion
2022-10-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Rivoceranib Small molecule
Subject pablizumab Unknown