drugset / Trial / NCT04971928
Phase 1 Study of GSK3228836 Pharmacokinetics in Participants With Hepatic Impairment
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This is a Phase 1, open-label, parallel-group study to evaluate the pharmacokinetics of GSK3228836 in participants with Child-Pugh B (CP-B) cirrhosis (moderate hepatic impairment), Child-Pugh A (CP-A) cirrhosis (mild hepatic impairment) and participants with normal hepatic function as healthy control.
Timeline
- Start
- 2021-09-07
- Primary completion
- 2022-05-12
- Completion
- 2022-05-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bepirovirsen | Antisense oligonucleotide | — | — |