drugset / Trial / NCT04973683

AL101 Before Surgery for the Treatment of Notch Activated Adenoid Cystic Cancer

NCT04973683

Phase 1 Completed 13 enrolled M.D. Anderson Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

This phase Ib trial studies the side effects and possible benefits of AL101 before surgery in treating patients with notch activated adenoid cystic cancer. AL101 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving AL101 before surgery may help to control adenoid cystic cancer that has a NOTCH pathway activation.

Timeline

Start
2021-09-30
Primary completion
2026-06-16
Completion
2026-06-16

Drugs

EvaluationDrugModalityDoseRoute
Subject AL101 Small molecule Intravenous