drugset / Trial / NCT04979221
Effect of Cyproheptadine on Ventilatory Support-free Days in Critically Ill Patients With COVID-19
RandomizedParallel-groupOpen-labelTreatment
Summary
This randomized controled open label clinical trial conducted in patients with hypoxemic respiratory failure admitted to the ICU and requiring ventilatory support (invasive or non-invasive) is to evaluate whether treatment with cyproheptadine, a serotonin receptor antagonist, compared to usual care, increases the number of ventilator-free days.
Timeline
- Start
- 2021-07-26
- Primary completion
- 2022-01-26
- Completion
- 2022-02-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyproheptadine | Small molecule | 8 mg | — |