drugset / Trial / NCT04979221

Effect of Cyproheptadine on Ventilatory Support-free Days in Critically Ill Patients With COVID-19

NCT04979221

Phase 3 Unknown 274 enrolled Hospital de Clinicas de Porto Alegre
RandomizedParallel-groupOpen-labelTreatment

Summary

This randomized controled open label clinical trial conducted in patients with hypoxemic respiratory failure admitted to the ICU and requiring ventilatory support (invasive or non-invasive) is to evaluate whether treatment with cyproheptadine, a serotonin receptor antagonist, compared to usual care, increases the number of ventilator-free days.

Timeline

Start
2021-07-26
Primary completion
2022-01-26
Completion
2022-02-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Cyproheptadine Small molecule 8 mg

Indications