drugset / Trial / NCT04983225
The Safety and Tolerability of Initial Periodontal Therapy Combined With Human Dental Pulp Stem Cell Injection in the Treatment of Chronic Periodontitis
RandomizedParallel-groupDouble-blindTreatment
Summary
The principal objective of this trial is to investigate the safety and tolerability of human dental pulp stem cells injection in the treatment of chronic periodontitis. The secondary objective is to provide the basis for dosage regimen for further clinical trials and to evaluate the preliminary efficacy.
Timeline
- Start
- 2021-07-31
- Primary completion
- 2024-07-31
- Completion
- 2024-08-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Human Dental Pulp Stem Cells | Cell therapy | 1e+06 cells | Other |
| Subject | Human Dental Pulp Stem Cells | Cell therapy | 5e+06 cells | Other |
| Subject | Human Dental Pulp Stem Cells | Cell therapy | 1e+07 cells | Other |
| Subject | Human Dental Pulp Stem Cells | Cell therapy | 2e+07 cells | Other |
| Subject | Human Dental Pulp Stem Cells | Cell therapy | 3e+07 cells | Other |
| Subject | Human Dental Pulp Stem Cells | Cell therapy | 4e+07 cells | Other |