drugset / Trial / NCT04989855

Fruquintinib Plus PD-1 Antibody in pMMR / MSS Locally Advanced Rectal Cancer (LARC) With High Immune Score

NCT04989855

Phase 2 Unknown 48 enrolled Sun Yat-sen University
NaSingle-groupOpen-labelTreatment

Summary

This is a prospective, one arm phase II study aimed to observe the efficacy and safety of tislelizumab combined with fruquintinib in treatment of patients with pMMR / MSS locally advanced rectal cancer with high immune score.

Timeline

Start
2021-08
Primary completion
2022-08
Completion
2024-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Fruquintinib Small molecule 5 mg
Subject Tislelizumab Monoclonal antibody 200 mg Intravenous

Indications

No indication recorded.