drugset / Trial / NCT04990284
eArly levoDopa With Opicapone in Parkinson's paTients wIth motOr fluctuatioNs.
RandomizedParallel-groupOpen-labelTreatment
Summary
This is a randomized, parallel group, multicentre, multinational, prospective, open-label exploratory study in Parkinson's disease (PD) patients to evaluate the add-on efficacy of opicapone 50 mg or an extra dose of levodopa (L-DOPA) 100 mg as first strategy for the treatment of wearing-off.
Timeline
- Start
- 2021-11-29
- Primary completion
- 2023-04-04
- Completion
- 2023-04-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | L-DOPA/DDCI | Unknown | 50 mg | Oral |
| Subject | Levodopa | Small molecule | 100 mg | Oral |
| Background | Carbidopa | Unknown | 25 mg | Oral |
| Background | benserazide | Small molecule | 25 mg | Oral |